K2 Biolabs is a Contract Research Organization (CRO). We provide full-service support for in vivo and in vitro needs and customized solutions from study conception to final data analysis.

No matter where you are in your research lifecycle, we can help.

Our Houston-based facility is custom-built to streamline processes and houses state-of-the-art laboratory facilities and high-value, specialized equipment to ensure quality data. We are proudly AAALAC-I® accredited and offer extensive vivarium services, all with the support of seasoned researchers and veterinarians. From cell-based assays to humanized models to data analysis, we have everything your team needs to ensure quality, compliance, and cost efficiency.

Our Full-Service Offerings at a Glance

In Vitro

  • Cancer cell lines
  • Human primary cells
  • Viral and nonviral gene modification
  • Cell-based assays
  • X-ray irradiation
  • Closed system and auto-processing methods

In Vivo

  • Surgical suites
  • Breeding and husbandry
  • Humanized models
  • Pharmacokinetics/ Pharmacodynamics (PK/PD) testing
  • Toxicity studies (chronic/acute)
  • Tissue distribution
  • X-ray irradiation
  • Good Laboratory Practice (GLP)


  • IVIS® imaging
  • Histology/ Immunohistochemistry (IHC)
  • Live cell imaging
  • Luminex multiplex
  • Western electrophoresis
  • Flow cytometry
  • Mass spectrometry
  • Gene expression analysis


Our AAALAC-I®–accredited vivarium has everything your trial could need. We can help design animal studies that are consistent with regulatory guidelines and then perform each step from conception through final data analysis and delivery.

The facility has capacity for 6000 rodents (with potential for growth), with seasoned veterinarians to oversee animal care and husbandry. Features include “passthroughs” to 4 procedure rooms as well as a surgical and necropsy suite.

In Vivo Capabilities and Techniques

  • On-site Institutional Animal Care and Use Committee (IACUC)
  • Toxicity studies
  • Anti-tumor efficacy models
  • PK/PD testing
  • Blood collection (retro-orbital bleeding [ROB], cardiac stick)
  • Oral gavage
  • Injections (IP, SC, IV, and RO)
  • Surgical techniques
  • Irradiation
  • IVIS imaging
  • Breeding
  • Euthanasia and necropsy
  • Others, as requested

Tissue Collection/Histology

  • Full necropsy suite(s)
  • Tissues (paraffin embedded blocks)
  • Advanced staining techniques and immunohistochemistry

Pharmacology Services

  • Cytokine/Chemokine multiplex analysis
  • Analysis via LC-MS/MS
  • ELISA, CBA, or ELISpot assays
  • Live cell analysis by flow cytometry
  • Gene expression analysis via qPCR/RNA-seq
  • Histological and immunological staining
  • PK/PD testing

Process Development

K2bio can support cell therapy process development, offering a combined 19 years of experience in developing and optimizing manufacturing processes for CAR-T, TCR-T, and TILs using both viral and nonviral gene delivery methods.

  • Cell isolation and processing
  • Cell activation optimization
  • Gene delivery and modifications
  • Scalable cell expansions
  • Cell enrichment
  • Formulation development
  • Quality assurance
  • Regulatory pathway navigation

Laboratory Operations

K2bio offers a wealth of additional services in the lab. Just a few are highlighted below, providing a glimpse into the array of resources available.

In Vitro: Cell Biology and Analysis

With our extensive menu of resources and capabilities, K2bio can fulfill your in vitro cell biology and analysis needs.

  • Oncology lines
  • Primary and stem cells
  • Xenografts
  • Molecular biology
  • Imaging
  • Media

In Vitro: Gene and Cell Therapy

K2bio can provide in vitro gene and cell therapy services including genetic modifications, cell production, and analysis using an array of advanced systems.

  • Retroviral production/transduction
  • Magnetic labeling/separation/elution
  • Multipanel flow panel design
  • Flow: FlowJo, Kaluza, Novoexpress
  • Cloning/Construct production
  • 3D co-culture live cell imaging (3 channel)
  • Antibody-specific binding analysis

Concierge Services

If a service isn’t readily available at K2bio, we will locate the right specialist to support your needs.


For more information, or to schedule a tour, please contact us.

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